Makram, E., Ibrahim, M., Abdel Rahman, A., aboraya, K. (2020). Serum Lactate/Albumin Ratio as a Predictor Of Morbidity and Mortality In Patients with Severe Sepsis and Septic Shock. Benha Medical Journal, 37(1), 220-228. doi: 10.21608/bmfj.2020.86205
Essam Makram; Mohamed Ibrahim; Ahmed Abdel Rahman; Karim aboraya. "Serum Lactate/Albumin Ratio as a Predictor Of Morbidity and Mortality In Patients with Severe Sepsis and Septic Shock". Benha Medical Journal, 37, 1, 2020, 220-228. doi: 10.21608/bmfj.2020.86205
Makram, E., Ibrahim, M., Abdel Rahman, A., aboraya, K. (2020). 'Serum Lactate/Albumin Ratio as a Predictor Of Morbidity and Mortality In Patients with Severe Sepsis and Septic Shock', Benha Medical Journal, 37(1), pp. 220-228. doi: 10.21608/bmfj.2020.86205
Makram, E., Ibrahim, M., Abdel Rahman, A., aboraya, K. Serum Lactate/Albumin Ratio as a Predictor Of Morbidity and Mortality In Patients with Severe Sepsis and Septic Shock. Benha Medical Journal, 2020; 37(1): 220-228. doi: 10.21608/bmfj.2020.86205
Serum Lactate/Albumin Ratio as a Predictor Of Morbidity and Mortality In Patients with Severe Sepsis and Septic Shock
1Department of Anaesthesia and Intensive Care, Benha Faculty of Medicine, Benha University
2department of nephrology and Internal medicine , Faculty of Medicine – Benha University,
Abstract
Background: Severe sepsis is common and frequently fatal and represents a significant health care burden. Sepsis is a syndrome of physiologic, pathologic, and biochemical abnormalities induced by infection. Aim of the work: This study examines the ability of serum lactate/albumin ratio to predict outcome regarding organ dysfunction and mortality in severe sepsis and septic shock. Materials and Methods: It is a prospective observational study conducted on 50 patients with severe sepsis and septic shock according to the (SCCM/ESICM/ACCP/ATS/SIS) International Sepsis Definitions Conference 2001 and fifty healthy age matched individuals as a control group. Results: Lactate/albumin ratio was higher on day 0 and 1 in the study group than in control group (p value <0.001). Also, it was significantly higher in patients that needed mechanical ventilation than patients who didn’t (p value p valuep value<0.001).Conclusion: Lactate/albumin ratio is a reliable biomarker for prediction of outcome as regards organ dysfunction and mortality in patients with severe sepsis and septic shock.
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