Assessment of Serum Level of Amyloid A in Patients with Acne Vulgaris

Articles in Press

Document Type : Original Article

Authors

1 Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University

2 Assistant Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University

3 Assistant Professor of Clinical and Chemical Pathology, Faculty of Medicine, Benha University

4 (M.B.B.Ch, Faculty of Medicine, Cairo University)

Abstract

Background: Serum Amyloid A (SAA) is a major acute phase protein produced in large quantity during Acute Phase Reactant (APR). The rise of SAA concentration in blood circulation during APR has been a clinical marker for active inflammation. This study aimed to evaluate serum levels of Amyloid A in patients with acne and its correlation with the disease severity. Methods: This prospective case-control study included 60 patients suffering from acne vulgaris. Patients were divided into 3 equal groups: Group A: patients with mild acne vulgaris. Group B: patients with moderate acne vulgaris. Group C: 20 patients with severe acne vulgaris. In addition, 30 apparently healthy, age and sex matched individuals were included as control group. Results: Serum Amyloid A level was significantly higher in the acne vulgaris group when compared to the control (mean=4.89 versus 1.08, p

Keywords

Benha Medical Journal

Articles in Press, Accepted Manuscript
Available Online from 30 April 2025

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