Role of Chemical Shift of MRI in Defining the Extent of Bone Tumors

Document Type : Original Article

Authors

1 Lecturer of Radiodiagnosis Faculty of Medicine -Benha University

2 Professor assistant Of Orthopedic Surgery Faculty of Medicine -Benha University

3 Department of Radiodiagnosis Faculty of Medicine -Benha University

Abstract

Background: Chemical shift imaging (CSI) is a valuable MRI technique that can aid in determining the extent of bone tumors by differentiating between tumor margins and surrounding red marrow or bone marrow edema. This study aimed to investigate whether chemical shift imaging is a useful addition to a tumor protocol for determining the extent of a skeletal tumor. Methods: This is a prospective study included 25 patients who have bone tumors and are candidates to MR imaging. The study was conducted at the radiology departments of the National Cancer Institute (NCI), Cairo University& Benha University hospital, Egypt. Patients underwent magnetic resonance imaging (MRI) with T1-weighted spin echo (T1SE), fluid-sensitive and CSI sequences. Tumor extent was recorded (in millimeters) on each sequence. Tumor extent on different sequences was compared. Results: The mean age of patients was 43 ±18.1 years and 15 patients (60%) were males, and 10 patients (40%) were females, the mean differences in the tumor extent between sequences were measured, there was good agreement between measurements of tumor extent on T1SE and CSI sequences in all cases (T1SE-CSI measurement difference range 0-1.4mm, P>0.05). Measurements from fluid sensitive sequences (T2WI and STIR) were significantly different from those of T1SE and CSI (P

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Benha Medical Journal
Volume 42, Issue 1
January 2025
Pages 12-22

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