Said, E., Fouad, Y., Abo-Amer, Y., Zidan, M., Kandil, A. (2024). Impact of Metabolic Associated Fatty Liver Disease on Health-Related Quality of Life. Benha Medical Journal, 41(8), 572-584. doi: 10.21608/bmfj.2024.289042.2078
Ebada Mohamed Said; Yaser Mahroos Fouad; Yousry Esam-Eldin Abo-Amer; Mohammed Soliman Zidan; Alaa El din Ibrahim Kandil. "Impact of Metabolic Associated Fatty Liver Disease on Health-Related Quality of Life". Benha Medical Journal, 41, 8, 2024, 572-584. doi: 10.21608/bmfj.2024.289042.2078
Said, E., Fouad, Y., Abo-Amer, Y., Zidan, M., Kandil, A. (2024). 'Impact of Metabolic Associated Fatty Liver Disease on Health-Related Quality of Life', Benha Medical Journal, 41(8), pp. 572-584. doi: 10.21608/bmfj.2024.289042.2078
Said, E., Fouad, Y., Abo-Amer, Y., Zidan, M., Kandil, A. Impact of Metabolic Associated Fatty Liver Disease on Health-Related Quality of Life. Benha Medical Journal, 2024; 41(8): 572-584. doi: 10.21608/bmfj.2024.289042.2078
Impact of Metabolic Associated Fatty Liver Disease on Health-Related Quality of Life
1Professor of Hepatology, Gastroenterology and Infectious Diseases Faculty of Medicine Benha University
2Professor of Gastroenterology, hepatology and Endemic medicine Faculty of Medicine, Minia University, Minia, Egypt
3Educational Assistant Consultant of Tropical Medicine Mahalla Hepatology Teaching Hospital
4M.B.B.Ch
5Assistant Professor of Hepatology, Gastroenterology, and Infectious Diseases Faculty of Medicine Benha University
Abstract
Introduction: Metabolic associated fatty liver disease (MAFLD), the nomenclature major benefit is the shift towards a diagnosis of inclusion based on the presence of metabolic dysfunction. MAFLD has also been associated with impaired health-related quality of life (HRQOL). Aim: to assess the impact of MAFLD & degree of hepatic steatosis and fibrosis on patients’ HRQOL applying the SF-36 Questionnaire. Methods: This cross sectional study was carried out on 250 adult who were subdivided into 2 groups, Group I (GI) comprised 150 consecutive patients with MAFLD while Group II (GII) comprised 100 apparently healthy subjects. Both studied groups had completed the short form-36 (SF-36) questionnaire. Results: The mean age among cases group was 43.6 ±10.5 years & females were the predominant. There was a highly statistical significance negative correlation between body mass index (BMI) and all domains of SF-36 questionnaire among GI. Scores of all scales of SF-36 were significantly lower in GI compared to GII). Hepatic steatosis grades with in GI according to CAP values were S1(17.3%), S2(37.3%) and S3(45.3). scores of all scales of SF-36 were significantly lower in S3 patients compared to S2 & S1(P value
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