Khalifa, A., Shebl, A., Farid, M., Gad, E. (2024). Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography. Benha Medical Journal, (), -. doi: 10.21608/bmfj.2024.253620.1973
Ahmed Morsy Khalifa; Ahmed Adel Shebl; Mohamed Fathy Farid; Elham Abdelazem Gad. "Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography". Benha Medical Journal, , , 2024, -. doi: 10.21608/bmfj.2024.253620.1973
Khalifa, A., Shebl, A., Farid, M., Gad, E. (2024). 'Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography', Benha Medical Journal, (), pp. -. doi: 10.21608/bmfj.2024.253620.1973
Khalifa, A., Shebl, A., Farid, M., Gad, E. Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography. Benha Medical Journal, 2024; (): -. doi: 10.21608/bmfj.2024.253620.1973
Effect of Smoking on Macular Perfusion Using Optical Coherence Tomography Angiography
1ophthalmology
Faculty of medicine –Benha University
2Lecturer of ophthalmology Faculty of medicine– Benha University
3Professor of ophthalmology Faculty of medicine –Benha University
4Assistant professor of ophthalmology Faculty of medicine –Benha University
Abstract
Objective: This study is designed to evaluate the effect of chronic smoking on macular perfusion using optical coherence tomography angiography (OCTA). Patients and methods: Forty patients participated in this prospective, controlled clinical investigation, which split them into two equal groups. For Group 1, we have long-time smokers who have been puffing away on at least 20 cigarettes daily for at least ten years (control group). All patients had their vision tested using a Decimal Notation chart, autorefractometers (Topcon type), slit-lamp anterior segment examinations, intraocular pressure measured using Goldmann applanation tonometry, dilated fundus examinations using 20D lenses, and (OCTA) with scan sizes of 6 mm 6 mm to determine foveal area zones (FAZ). Results: Smokers had significantly lower mean densities across the board (Superficial layer), in the upper and lower halves of the brain, and in the cerebral hemispheres. has a very small P-value (less than 0.001). Smokers had significantly lower mean values for total (Deep layer) density, hemi superior density, and hemi inferior density than nonsmokers. Having a statistically significant P-value of 0.001 The smokers' group had a significantly larger mean FAZ area (mm2) compared to the controls (P0.001). Conclusions: DCP's is more vulnerable to oxidative damage and poor perfusion brought by cigarette smoking, which led to a considerable drop in VD of DCP compared to SCP. In addition, bigger research examining the long-term effect of smoking on retinal microcirculation in the macula may help clarify the significance of smoking as a risk factor for systemic vascular diseases.