M. El Hammady, A., A.Khalil, M., Marei, Y., Mohammed Ahmed, M., Mogahed, M. (2024). Role of Hypovitaminosis D in Diabetes-Related Anemia of Chronic Disease and Value of Its Replacement in Response to Therapy: A Randomized Control Trial. Benha Medical Journal, (), -. doi: 10.21608/bmfj.2024.274818.2035
Amr M. El Hammady; Medhat A.Khalil; Yomna Mohamed Marei; Mahasen Hamdy Mohammed Ahmed; Mysara Mohamed Mogahed. "Role of Hypovitaminosis D in Diabetes-Related Anemia of Chronic Disease and Value of Its Replacement in Response to Therapy: A Randomized Control Trial". Benha Medical Journal, , , 2024, -. doi: 10.21608/bmfj.2024.274818.2035
M. El Hammady, A., A.Khalil, M., Marei, Y., Mohammed Ahmed, M., Mogahed, M. (2024). 'Role of Hypovitaminosis D in Diabetes-Related Anemia of Chronic Disease and Value of Its Replacement in Response to Therapy: A Randomized Control Trial', Benha Medical Journal, (), pp. -. doi: 10.21608/bmfj.2024.274818.2035
M. El Hammady, A., A.Khalil, M., Marei, Y., Mohammed Ahmed, M., Mogahed, M. Role of Hypovitaminosis D in Diabetes-Related Anemia of Chronic Disease and Value of Its Replacement in Response to Therapy: A Randomized Control Trial. Benha Medical Journal, 2024; (): -. doi: 10.21608/bmfj.2024.274818.2035
Role of Hypovitaminosis D in Diabetes-Related Anemia of Chronic Disease and Value of Its Replacement in Response to Therapy: A Randomized Control Trial
1Assistant Professor of Internal Medicine, Faculty of Medicine, Benha University
2Assistant Professor of Internal Medicine, Faculty of Medicine, Benha University
3Lecture of Internal Medicine, Faculty of Medicine, Benha University
4Departmet of Internal Medicine
Faculty of Medicine- Benha University
Abstract
Background: Deficiency of vitamin D has become a global public health problem, with nearly 1 billion people worldwide being in a state of vitamin D insufficiency or deficiency. The aim of this work was to evaluate the role of hypovitaminosis D in diabetes- related anemia of chronic disease and value of its replacement in response to therapy. Methods: This randomized control trial included patients with diabetes- related anemia of chronic disease), the least Number is 318 patients. The three groups were randomized equally; group 1 was with diabetes- related anemia of chronic disease) with normal 25 hydroxy vitamin D and received treatment for anemia, group 2 was with diabetes- related anemia of chronic disease with low level of 25 hydroxy vitamin D, and group 3 was with diabetes but no anemia then follows up for hemoglobin concentration. Those Patients were informed about using vitamin D in treatment (benefits and side effects) in addition to treatment of specific anemia, then we assessed anemia after three months . Results: The study found no significant difference in age, sex, or type of diabetes mellitus (DM) between groups. However, individuals with anaemia, particularly those with low vitamin D levels, had lower serum iron and TIBC levels and higher ferritin levels. Vitamin D levels were negatively correlated with ferritin and positively correlated with iron and TIBC. HbA1C levels had negative correlations with iron, TIBC, and WBCs.Conclusions: The current study suggested that there was close relationship between vitamin D deficiency and anemia in diabetic patients.