Ismail Ibrahim, S., Abdelrahman, E., Hagr, M., Rezk, E. (2024). The outcome of using first oral funny current inhibitor drug in septic shock patients. Benha Medical Journal, 41(2), 128-140. doi: 10.21608/bmfj.2024.252286.1965
Samir El-Sayed Ismail Ibrahim; Ehab Ahmed Abdelrahman; Muhammad Muhammad Hagr; Emad Fawzy Rezk. "The outcome of using first oral funny current inhibitor drug in septic shock patients". Benha Medical Journal, 41, 2, 2024, 128-140. doi: 10.21608/bmfj.2024.252286.1965
Ismail Ibrahim, S., Abdelrahman, E., Hagr, M., Rezk, E. (2024). 'The outcome of using first oral funny current inhibitor drug in septic shock patients', Benha Medical Journal, 41(2), pp. 128-140. doi: 10.21608/bmfj.2024.252286.1965
Ismail Ibrahim, S., Abdelrahman, E., Hagr, M., Rezk, E. The outcome of using first oral funny current inhibitor drug in septic shock patients. Benha Medical Journal, 2024; 41(2): 128-140. doi: 10.21608/bmfj.2024.252286.1965
The outcome of using first oral funny current inhibitor drug in septic shock patients
1Assistant Professor of Anesthesia and intensive care, Faculty of Medicine, Benha University
2Professor of Anesthesia and intensive care, Faculty of Medicine, Benha University
3Critical care medicine Department, Faculty of Medicine, Benha University, Egypt
4Lecturer of Critical care medicine, Faculty of Medicine, Benha University
Abstract
Background: Septic shock is a subtype of sepsis that is clinically identified by a requirement for the administration of vasopressors to increase the mean arterial blood pressure to 65 mmHg or greater despite sufficient fluid resuscitation, or by an increase in serum lactic acid levels by 2 mmol/L or greater. This study aimed to evaluate the effect of the cardiac pacemaker current inhibitor ivabradine on heart rate and outcome in patients with septic shock. Methods: A prospective, single blinded randomized controlled clinical trial study conducted on 102 septic shock patients. Results: regarding regression analysis indicated that Age, APACHE II, Sofa at (4th, 7th day), MAP at 4th day, NE at (4th, 7th day), HR at 4th day and ICU stay was the most factor affected mortality rate in patients with septic shock (P
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