Prevalence of Thyroid Disorders among Pregnant Women in Banha City, Egypt a Hospital Based Cross Section Study

Document Type : Original Article

Authors

Internal Medicine Department, Faculty of Medicine, Benha University, Benha, Egypt.

Abstract

Background: Thyroid disorders rank as one of the prevailing endocrine disorders frequently observed during the course of pregnancy. This study assessed the thyroid disorders frequency among pregnant women residing in Banha City, Egypt, elucidating the types of disorders, their distribution across trimesters, and potential correlations with demographic factors, obstetric history, and thyroid function test results. Methods: This Cross Section Study included 173 pregnant females with abnormal thyroid function. A comprehensive history, and a thorough clinical examination were conducted [demographic data, drugs, obstetric history, previous pregnancy outcome and complication, manifestation on thyroid dysfunction and family history of thyroid diseases], lab investigation [serum TSH serum freeT3 & serum freeT4, TSH value of American Thyroid Association (ATA) 2011]. Results: According to abortion history, overt hyperthyroidism is more likely to have a higher number of abortions compared to those with gestational or subclinical hyperthyroidism (p=0.007). There was significant higher median number of abortions in overt hyperthyroidism group compared with gestational hyperthyroidism group (p=0.033), although a significant higher median number of abortions in overt hyperthyroidism group compared with subclinical hyperthyroidism group (p=0.002). overt hypothyroidism was more likely to have a higher number of abortions compared to those with isolated maternal hypothyroxinemia or subclinical hypothyroidism (p < 0.001). Conclusion: Demographic factors and obstetric history showed limited associations with the types of thyroid disorders. However, specific thyroid function test parameters [TSH, Free T3, and Free T4] revealed significant correlations with various subtypes of thyroid disorders, showing their diagnostic relevance in identifying and characterizing these conditions during pregnancy.

Keywords

Benha Medical Journal
Volume 41, Issue 2
May and June 2024
Pages 141-150

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