Role of Myocardial Strain Analysis by 2-Dimensional Speckle Tracking Echocardiography in Assessment of Severity of Coronary Artery Stenosis in Coronary Artery Disease Patients

Ebaid, Hany H.; Mohamed, Kareem Anwar; Hamoda, Mohamed Ahmed; Mahmoud, Marwa Kamal

doi:10.21608/bmfj.2023.236981.1900

Role of Myocardial Strain Analysis by 2-Dimensional Speckle Tracking Echocardiography in Assessment of Severity of Coronary Artery Stenosis in Coronary Artery Disease Patients

Document Type : Original Article

Authors

¹ Assistant professor of cardiovascular medicine Faculty of medicine – Benha University

² Department of cardiovascular medicine Faculty of medicine &ndash; Benha University

³ Assistant Professor of cardiovascular medicine Faculty of medicine – Benha University

⁴ Lecturer of cardiovascular medicine Faculty of medicine – Benha University

10.21608/bmfj.2023.236981.1900

Abstract

Background:
Myocardial strain analysis with 2D-speckle-tracking echocardiography, which is performed at resting position, offers valuable information about myocardial fiber changes in different types of myocardial diseases.
Aim: This study evaluated the role of myocardial strain analysis in assessment of severity of coronary artery stenosis in coronary artery disease patients.
Patients and methods: This study included 150 patients with suspected CAD, 50 patients were with Non-ST elevation ACS and 100 patients underwent stress ECG, 50 patients of them showed positive or equivocal stress ECG. patients were divided into two groups: Group A: 50 Patients with Non-ST elevation Acute coronary syndrome (NSTACS).and Group B: 50 Patients with positive or equivocal stress ECG. (Stable coronary artery disease). All patients underwent full history & examination, ECG, conventional & speckle tracking Echocardiography & both Gensini & Syntax scores were calculated for every patient.
Results: The study revealed a significant lower GLPSS in Group A compared to Group B (p < 0.001). Also as regard the correlation of TLS and significant CAD lesion in each Coronary Artery Territories, a significant higher TLS correlated with significant lesion in LAD and LCX compared to non-significant lesions in Group A (P value= 0.001) While in Group B a significant higher TLS correlated with significant lesion in LAD, LCX and RCA compared to non-significant lesions (P value= 0.001)
Conclusion: LVGLS and TLS have an incremental prognostic value and can be used to assess the severity of coronary stenosis in patients with coronary artery disease.

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