Prognostic value of Red Blood Cells Distribution Width in Acute Kidney Injury in PICU

Document Type : Original Article

Authors

1 Pediatric Department, Faculty of Medicine, Benha University, Egypt.

2 Department of Pediatrics, Faculty of Medicine, Benha University, Egypt.

3 department of clinical and chemical pathology faculty of medicine benha university

4 Department of pediatrics, elsinbillwin general hospital, ministry of health, Egypt

Abstract

Background: RDW predicts short-term outcome in critically unwell AKI patients. RDW's long-term all-cause mortality prognostic value in children is unknown . Methods: 100 PICU patients was studied in PICU Benha university. Clinical Pathology Department Benha University undertook laboratory tests. Scoring system used in this study are SOFA score which is a straightforward and objective measure to calculate organ dysfunction in six organ systems , APSIII score , RIFLE score and KDIGO classification . Results: RDW > 15.45 had 81.5% sensitivity and 60.3% specificity for predicting mortality. Statistically significant (p 0.001) Septic shock, high GCS, high SOFA score, high APS III, high initial blood creatinine, and high initial RDW are death risk factors. The higher initial serum creatinine wasn't an independent risk factor in multivariate regression analysis. RDW, KDIGO and RIFLE criteria had no correlation . Conclusion: Higher RDW was associated with increased mortality in critically ill AKI patients. Large prospective trials with longer follow-Ups must corroborate our findings.

Keywords

Benha Medical Journal
Volume 41, Special issue (Pediatrics)
January and February 2024
Pages 40-50

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