Awareness among Patients Regarding Drug Dose Adjustment in Chronic Kidney Disease

Document Type : Original Article

Authors

1 Assistant professor of internal medicine Faculty of Medicine - Benha University

2 lecturer of internal medicine Faculty of Medicine - Benha University

3 Internal Medicine Department, Faculty of Medicine, Benha University, Benha, Egypt

4 benha university faculty of medicine internal medicine department

Abstract

Background: Inappropriate medication dosing in patients with chronic kidney disease can cause toxicity or ineffective therapy. Patients are at a high risk of developing related adverse events caused by the altered effect of drugs in conjunction with the use of polypharmacy to treat comorbid conditions.
Aim: The aim of this work was to highlight the awareness among patients regarding dose adjustment in chronic kidney disease.
Methods: This was cross-sectional study was carried out in Benha University hospitals in internal medicine department, cardiology, hepatology, pulmonology, and neuropsychiatry department on different doctors and patients in ward in internal medicine department and a questionnaire were done including the following items: Demographic information, Occupational history, Education history, and Personal/family history of kidney disease.
Results: Regarding questions asked to patients 55% knew that patients with CKD need dose adjustment, 14% knew drugs need to be adjusted and 9% knew Percentage of drugs adjusted
Conclusions: Patients across all levels of training demonstrated poor awareness and knowledge of individualizing therapy based on patient’s renal function. Poor knowledge of renal dosing rules and lack of medication information have been identified as major causes of prescribing errors.

Keywords

Benha Medical Journal
Volume 40, Annual conference issue
March and April 2023
Pages 213-224

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