Hematological Changes with Covid-19 and Post Covid-19 Syndrome and Its Outcome In Hospitalized Children in Benha Children Hospital

Assar, Effat Hussein; ElBakry, Mohamed Mostafa; Akl, Hanan El Sayed; Abd El Rashid, Sabah Gamal; Rachwan, Maha M.Taher; Afifi, Ahmed RSA

doi:10.21608/bmfj.2023.183560.1736

Hematological Changes with Covid-19 and Post Covid-19 Syndrome and Its Outcome In Hospitalized Children in Benha Children Hospital

Document Type : Original Article

Authors

¹ Pediatric department;faculty of medicine;Benha University;Qalyubia

² Pediatric Department Faculty of Medicine Benha University

³ Pediatric Department, Faculty of Medicine, Benha University, Egypt

⁴ clinical pathology department, Faculty of Medicine, Benha University, Egypt

10.21608/bmfj.2023.183560.1736

Abstract

Aim: Our goal is examining the correlation between illness severity and Covid-19's impact on the child's complete blood count and hematological alterations, as well as to assess the impact of these changes on the child's progression and prognosis.
Methods: combined a retrospective look at data with a projected look at the same data. It was at the isolation covid department of Benha Children's Hospital that this research took place. The time frame for this research was from January of 2021 through December of the same year. All patients diagnosed with COVID-19 or post-COVID MIS-C/Kawasaki were included in the study.
Results: mean age was statistically significant higher among negative COVID 19 group than positive group (p=0.03). Mean HB and HCT % were statistically significant higher among negative COVID 19 group than positive group (p=0.02 and 0.03 respectively), Mean D-dimmer, S-ferritin and L D H were statistically significant higher among positive COVID 19 group than negative group (p < 0.001). Positive contact results was statistically significant higher among positive COVID 19 (58.4%) group than negative group (14.8%) (p < 0.001). Less than 1 year old age was statistically significant higher among positive COVID 19 (61%) group than negative group (45.7%) (p=0.02).
Conclusion: Diagnosing COVID-19 and determining prognosis may be aided by testing blood parameters. Shifts in the lymphocyte count are not readily apparent in children. However, D-dimer levels are elevated in COVID-19-infected children. Abnormal hematological parameters are one way in which COVID-19 might manifest itself, and they can serve as early evidences for diagnosis and prognosis.

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