Abdel Haie, O., El.Sabbagh, G., Elsayed, A., AbdElatty, R. (2024). Predictors Of Mortality In Outborns With Neonatal Sepsis:Aprospective Observational Study. Benha Medical Journal, 41(Special issue (Pediatrics)), 19-29. doi: 10.21608/bmfj.2023.170637.1693
Omima mohamed Abdel Haie; Ghada Gamal El.Sabbagh; Adel shebl Elsayed; Rania I. AbdElatty. "Predictors Of Mortality In Outborns With Neonatal Sepsis:Aprospective Observational Study". Benha Medical Journal, 41, Special issue (Pediatrics), 2024, 19-29. doi: 10.21608/bmfj.2023.170637.1693
Abdel Haie, O., El.Sabbagh, G., Elsayed, A., AbdElatty, R. (2024). 'Predictors Of Mortality In Outborns With Neonatal Sepsis:Aprospective Observational Study', Benha Medical Journal, 41(Special issue (Pediatrics)), pp. 19-29. doi: 10.21608/bmfj.2023.170637.1693
Abdel Haie, O., El.Sabbagh, G., Elsayed, A., AbdElatty, R. Predictors Of Mortality In Outborns With Neonatal Sepsis:Aprospective Observational Study. Benha Medical Journal, 2024; 41(Special issue (Pediatrics)): 19-29. doi: 10.21608/bmfj.2023.170637.1693
Predictors Of Mortality In Outborns With Neonatal Sepsis:Aprospective Observational Study
1Assistant Professor of Pediatric Faculty of Medicine – Benha University
2Department of Pediatric
Faculty of Medicine – Benha University
3Professor of Pediatric Faculty of Medicine – Benha University
4Department of Paediatrics- Faculty of Medicine-Benha University
Abstract
Background:Mortality in outborns with Neonatal sepsis result from interaction of maternal-feotal colonization,transplacental immunity and physical and cellular defence mechanisms of neonates.Objective:The objective of this study was to determine risk factors 0f mortality in outborn with neonatal sepsis.Materials and Methods:A 6-months prospective observational study was done at neonatal intensive care unit of benha university hospital and serselyan general hospital.All outborn neonates with maternal and neonatal risk factors of sepsis were enrolled. Blood culture ,sepsis screen and other needed investigations were performed.Results:The mortality rate among outborn with neonatal sepsis was42%.The common presentations among outborns with neonatal sepsis were Hypothermia,convulsions,cyanosis and poor suckling.The,significant risk factors of mortality include Malesex(p=0.021),gestationalage(p=0.027), presence of convulsions(p=0.003), cyanosis(p=0.02), hypothermia(p=0.009), mottling(p=0.001),poor suckling(p=0.001),positive c- reactive protein(p=0.009), Anemia(p=0.011)..Maternal factors such as Premature rupture of membranes(p=0.047) and hypertension during pregnancy(p=0.001)and diabetes mellitus(p=0.017) were statistically significant associated with mortality in outborn neonatal sepsis.On multivariate logistic regression Temprature on admission and distance during transport to hospital were the predictive factors of mortality in outborn neonatal sepsis.Conclusion:Long distance tranelled with neonates during transport to hospital and presentation with hypothermia at admistion , were the independent risk factors of mortality in outborn neonatal sepsis.
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