The Role of Optical Coherence Tomography Angiography to Assess Retinal Perfusion of Non-Proliferative Diabetic Retinopathy

Document Type : Original Article

Authors

1 ophthalmology department,faculty of medicine,Benha university,Benha,egypt

2 ophthalmology department, faculty of medicine, benha university, benha, egypt

Abstract

Background: Diabetic retinopathy (DR) is one of the leading causes of visual impairment and blindness in patients aged 20-47. Clinically, DR has two stages: non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR). The aim of this work was to assess retinal microvasculature abnormalities in different stages of non-proliferative diabetic retinopathy using optical coherence tomography angiography.
Methods: This cross-sectional case control study was carried out on 90 eyes of 55 subjects attending outpatient clinic of Ophthalmology department (35 of healthy non-diabetic, 15 of mild NPDR, 27 of moderate NPDR and 13 of severe NPDR).
Results: At 3x3 size scan of OCTA, FAZ and PERIM were significantly more enlarged in case group compared to the control group (both p < 0.001) however, superficial and deep VD% were significantly lower in case group compared to the control group (both p < 0.001). There was a significant difference among the three subgroups (mild, moderate and severe) as regards FAZ, superficial and deep VD% (all p < /p>

Keywords

Benha Medical Journal
Volume 40, Special issue (Surgery)
January and February 2023
Pages 320-335

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