Assar, E., El ghaiaty, H., ismail, Y., Arafa, R., hassan, R. (2022). Evaluation of severity and prognosis of transient tachypnea of newborn and its relation to Mean platelet volume. Benha Medical Journal, 39(3), 890-903. doi: 10.21608/bmfj.2022.161855.1664
Effat Hussein Assar; Hesham El ghaiaty; yasser mahmoud ismail; Raghda Mohamed Arafa; Rasha aguib hassan. "Evaluation of severity and prognosis of transient tachypnea of newborn and its relation to Mean platelet volume". Benha Medical Journal, 39, 3, 2022, 890-903. doi: 10.21608/bmfj.2022.161855.1664
Assar, E., El ghaiaty, H., ismail, Y., Arafa, R., hassan, R. (2022). 'Evaluation of severity and prognosis of transient tachypnea of newborn and its relation to Mean platelet volume', Benha Medical Journal, 39(3), pp. 890-903. doi: 10.21608/bmfj.2022.161855.1664
Assar, E., El ghaiaty, H., ismail, Y., Arafa, R., hassan, R. Evaluation of severity and prognosis of transient tachypnea of newborn and its relation to Mean platelet volume. Benha Medical Journal, 2022; 39(3): 890-903. doi: 10.21608/bmfj.2022.161855.1664
Evaluation of severity and prognosis of transient tachypnea of newborn and its relation to Mean platelet volume
1Pediatric department;faculty of medicine;Benha University;Qalyubia
2paediatrics department, faculty of medicine, benha university
3clinical pathology department - faculty of medicine - benha univeristy
4Pediatric medicine benha university benha Egypt
5Lecturer of Pediatrics Faculty of Medicine - Benha University
Abstract
Background: Transient tachypnea of the newborn (TTN) is a common cause of respiratory distress in late preterm and term infants and is generally a benign disease treated with a brief course of oxygen. Platelets contribute to the basal barrier integrity of the alveolar capillaries, which selectively restricts the transfer of water, proteins, and red blood cells out of the vessels. This study aimed to evaluate the role of mean platelet volume (MPV) in predicting the severity of TTN and its outcome. Methods: This study included 60 neonates. They were divided into two groups; Group 1 including 20 newborns with tachypnea for 48 h. Group 2 was subdivided into 2 subgroups; Group 2A including 20 newborns who needed only oxygen therapy and Group 2B including 20 newborns who needed ventilator support. ROC analysis was done to assess the performance of laboratory investigations associated with tachypnea> 48 hours. Results: Regarding platelet count; AUC was 0.756 (95% confidence interval: 0.634-0.878), p=0.001. At a cutoff point