Optical Coherence Tomography Angiography in Exudative Age-related Macular Degeneration

Document Type : Original Article

Authors

1 Ophthalmology department, Faculty of Medicine; Helwan University.

2 Ophthalmology Department, Faculty of medicine; Ain Shams University.

3 Lecturer of Ophthalmology department, Faculty of medicine, Helwan University.

Abstract

Aim: To determine specificity and sensitivity of OCT-A in detecting choroidal neovascular lesions (CNV) in eyes with suspected nAMD.
Setting: Al Mashreq Eye Center, in the period between Jul-2021 to Nov-2021.
Methods: A prospective, comparative study included 44 eyes to assess accuracy of OCT-A in the detection of nAMD compared to conventional OCT. Eyes were divided into a study group with nAMD, and a control group with dry AMD. OCT of the central macula was conducted, followed by OCT-A.
Results: This study was performed on 25 patients with a mean age of 69.88 ± 8.31 years. The mean BCVA was 0.45 (± 0.31), and that of SE was 0.16 (± 1.52). IOP had a mean of 15.39 (± 3.08).
According to SD-OCT criteria; 24 eyes (54.5%) were diagnosed as dry AMD, and 20 eyes (45.5%) with nAMD. Cases of nAMD were subdivided into type-1 (70%), and type-2 (30%). For eyes with type 1, 8 cases (57.1%) had an associated fibrovascular PED. Using OCT-A, 28 eyes were classified as dry AMD, and 16 eyes with nAMD that were differentiated into: Type-1 (6-cases), Type-1 with PED (5-cases) and Type-2 (5-cases). There was no statistically significant difference between OCT and OCT-A regarding percentage of positive cases (p=0.386), and their finding of type-1, type-1 with PED, and type-2 (p=1.000).
Conclusion:
There was a statistically significant relation in classification agreement between SD-OCT and OCT-A findings (p < /p>

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