25-HYDROXY VITAMIN D SERUM LEVEL IN CHILDREN WITH CONGENITAL HEART DISEASE

Document Type : Original Article

Authors

1 Lecturer of Pediatrics Faculty of Medicine - Benha University

2 Department of Paediatrics-Faculty of Mediicine-Benha University

3 department of clinical and chemical pathology faculty of medicine benha university

4 MBBCH

Abstract

Background & Aim: Identification of 25(OH) Vit D receptors in endothelial cells, smooth muscle cells, and myocytes from the heart has led to the hypothesis that this 25(OH) Vit D is involved in cardiovascular disease. The present study was designed to evaluate 25-hydroxy Vitamin D serum levels in congenital heart disease (CHD) children compared to controls. Methods: This case control study included 100 children, divided into 2 groups, Group (A) included 60 children with CHD who were divided into two groups (cyanotic and acyanotic). And group (B) included 40 apparently healthy children as a control group. All patients included in the study were subjected to the following: complete history taking and physical examination, echocardiography, and serum 25 (OH) vitamin D levels. Results: The mean serum.25 (OH) vitamin D level was significant lower in the CHD group than control group . the Serum.25 (OH) vitamin D level was significant lower in cyanotic group than acyanotic patients . there were a statistically significant difference between Serum.25 (OH) vitamin D level with various age groups of cyanotic and acyanotic patients. Conclusion: The serum level of 25(OH) Vit D was lower in CHD children, and among the patients, was lower in cyanotic. So it should be checked in CHD children especially those who suffered from cyanotic heart disease.

Keywords

Benha Medical Journal
Volume 39, Issue 2
July and August 2022
Pages 602-610

Files

Share

How to cite

Statistics