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AlFiqi, O., Khashaba, R., Youssef, A., Abd ElMaksoud, S. (2022). Pro-oxidant /antioxidant balance in neonatal jaundice pre and after phototherapy. Benha Medical Journal, 39(2), 418-428. doi: 10.21608/bmfj.2022.123338.1549
Osama AlFiqi; Rana Khashaba; Amal Saeed Youssef; Shaima Reda Abd ElMaksoud. "Pro-oxidant /antioxidant balance in neonatal jaundice pre and after phototherapy". Benha Medical Journal, 39, 2, 2022, 418-428. doi: 10.21608/bmfj.2022.123338.1549
AlFiqi, O., Khashaba, R., Youssef, A., Abd ElMaksoud, S. (2022). 'Pro-oxidant /antioxidant balance in neonatal jaundice pre and after phototherapy', Benha Medical Journal, 39(2), pp. 418-428. doi: 10.21608/bmfj.2022.123338.1549
AlFiqi, O., Khashaba, R., Youssef, A., Abd ElMaksoud, S. Pro-oxidant /antioxidant balance in neonatal jaundice pre and after phototherapy. Benha Medical Journal, 2022; 39(2): 418-428. doi: 10.21608/bmfj.2022.123338.1549

Pro-oxidant /antioxidant balance in neonatal jaundice pre and after phototherapy

Article 8, Volume 39, Issue 2, July and August 2022, Page 418-428  XML PDF (454.05 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2022.123338.1549
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Authors
Osama AlFiqi1; Rana Khashabaorcid 2; Amal Saeed Youssef email 3; Shaima Reda Abd ElMaksoud1
1Department of Pediatrics, Benha Faculty of Medicine, Benha University, Benha, Egypt
2Department of Clinical Pathology and Chemistry, Benha Faculty of Medicine, Benha University, Benha, Egypt
3MBBCH
Abstract
Background and Aim: This prospective observational study was designed aiming at evaluation of the possible effect of phototherapy on pro-oxidant/antioxidant balance (PAB) in newborns with jaundice. Patients and Methods: This study included forty newborns admitted to the NICU of Benha University Hospitals. The patients were full term, weighing > 2500 gm, aged between 2 and 14 days, with idiopathic unconjugated hyperbilirubinemia (bilirubin levels > 15 mg/dl) and were treated with phototherapy. All the studied patients were subjected to full medical history taking, complete clinical examination, and laboratory investigations as: complete blood count, ABO and Rh group, serum bilirubin total, direct and indirect, and PAB. Follow up investigations of serum total bilirubin (STB) levels, and PAB were recorded at the end of the phototherapy process. Results: The median pro-oxidant significantly increased after phototherapy (52.5 nmol/L) than before it (31.8 nmol/L) (P-value
Keywords
phototherapy; Pro-oxidant; antioxidant; PAB; Jaundice
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