Background: Osteoarthritis (OA) is most prevalent type of arthritis, which significantly affects the patient’s mobility complex. The aim to evaluate the evidence from the literature regarding the superiority of platelet-rich plasma (PRP), hyaluronic acid (HA), or corticosteroids (CS) over each other's. Methods: An electronic search was coducted between January 2010 to March 2021 in different databases; PubMed, SCOPUS, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL). Included randomized, nonrandomized trials that were published in English with full text available. Results: From a total 6912 screened citations, thirty studies met our inclusion criteria with a total 3303 cases. Most on included studies (N=13) compared platelet-rich plasma to hyaluronic acid and six studies compared hyaluronic acid to cortico-steroids, four studies compared hyaluronic acid to hyaluronic acid + cortico-steroids , one study compared platelet-rich plasma to cortico-steroids and another study compared platelet-rich plasma to hyaluronic acid acid , cortico-steroids. Regarding platelet-rich plasma compared to hyaluronic acid, evidence favored platelet-rich plasma over hyaluronic acid in majority of studies, the effect of platelet-rich plasma lasted longer up to 12 months, and it might be extended to 18 months if intra-osseous injection would be considered. On the other hand, hyaluronic acid should moderate efficacy over cortico-steroids injection but its effects survived only up to six months. Conclusion; platelet-rich plasma is most effective type on the long term and it provides pain relief up to 12 months especially in cases with low grades osteoarthritis and young age patients.
El sayed, M., Halawa, A., kandil, M., & Shenoda, A. (2022). Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review. Benha Medical Journal, 39(1), 191-203. doi: 10.21608/bmfj.2021.90036.1455
MLA
Magdy El sayed; Abdelsamie Halawa; Mahmoud kandil; Androw Shenoda. "Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review", Benha Medical Journal, 39, 1, 2022, 191-203. doi: 10.21608/bmfj.2021.90036.1455
HARVARD
El sayed, M., Halawa, A., kandil, M., Shenoda, A. (2022). 'Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review', Benha Medical Journal, 39(1), pp. 191-203. doi: 10.21608/bmfj.2021.90036.1455
VANCOUVER
El sayed, M., Halawa, A., kandil, M., Shenoda, A. Effectiveness of Different Types of Intraarticular Injections for the Knee Osteoarthritis; a Systemic Review. Benha Medical Journal, 2022; 39(1): 191-203. doi: 10.21608/bmfj.2021.90036.1455
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