Barakat, E., Habeeb, M., Abbas, N. (2021). Role of NBI and WLE in diagnosis of Barrett’s esophagus in patients with chronic gastroesophageal reflux disease. Benha Medical Journal, 38(1), 407-418. doi: 10.21608/bmfj.2021.51085.1348
Enass AME Barakat; Maha Habeeb; Neven Farouk Abbas. "Role of NBI and WLE in diagnosis of Barrett’s esophagus in patients with chronic gastroesophageal reflux disease". Benha Medical Journal, 38, 1, 2021, 407-418. doi: 10.21608/bmfj.2021.51085.1348
Barakat, E., Habeeb, M., Abbas, N. (2021). 'Role of NBI and WLE in diagnosis of Barrett’s esophagus in patients with chronic gastroesophageal reflux disease', Benha Medical Journal, 38(1), pp. 407-418. doi: 10.21608/bmfj.2021.51085.1348
Barakat, E., Habeeb, M., Abbas, N. Role of NBI and WLE in diagnosis of Barrett’s esophagus in patients with chronic gastroesophageal reflux disease. Benha Medical Journal, 2021; 38(1): 407-418. doi: 10.21608/bmfj.2021.51085.1348
Role of NBI and WLE in diagnosis of Barrett’s esophagus in patients with chronic gastroesophageal reflux disease
Mansoura University Faculty of Medicine Internal Medicine Department Gastroenterology and Hepatology Unit
Abstract
Abstract: Background: Recent data have emerged that a targeted biopsy technique using Narrow-Band Imaging (NBI) could be considered in patients undergoing surveillance for Barrett’s esophagus (BE). Aim of the study: to determine the role of NBI versus conventional- white light endoscopy (WLE) in diagnosis of Barrett’s esophagus Subjects and methods: the study included 274 patients with chronic reflux symptoms, conventional- white light endoscopy (WLE) was done in all cases for diagnosis of BE, 4-random biopsies were taken and examined by histopathology for detection of columnar-lined intestinal metaplasia, patients tested negative were re-examined by NBI and targeted biopsy were taken in patients for confirmation of presence of intestinal metaplasia. Results: 90 patients had columnar-lined epithelium (CLE) by WLE (32.8%); Seventy- three patients with 4 quadrant biopsy technique confirmed to have intestinal metaplasia (81.1% of cases with endoscopic BE, and 26.6% of all screened patients), 17 patients with negative histopathology for BE were re-examined endoscopically and NBI - targeted biopsies were taken, 7 patients of them showed intestinal metaplasia, so total patients confirmed to have BE has risen to 80 patients (88.9%). Conclusion: NBI- targeted biopsies could diagnose BE in patients tested negative by WLE taken biopsies