Role of Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) and Apparent Diffusion Coefficient (ADC) in Evaluation of Urinary Bladder Cancer

Document Type : Original Article

Authors

1 Department of radiology Benha faculty of medicine, Benha University, Egypt

2 Department of radiology, urology and nephrology center, Mansoura university, Egypt.

Abstract

Background: Urinary bladder cancer (BC) is reported as the 2nd most common genitourinary cancer in males and the 9th most common in females. Accurate pre-surgical evaluation of the local stage of the bladder cancer is crucial in the treatment strategy. So it is very important to evaluate and no invasive imaging modality to help accurate staging of the disease. Purpose:To evaluate role of diffusion weighted MR imaging (DW-MRI) in detection, T-staging of urinary bladder carcinoma.Patients and methods: During the period between November 2018 and November 2019, 44 patients (36 males and 8 females) presenting with haematuria, lower urinary symptoms and urinary bladder mass detected by ultrasound, were enrolled prospectively. All patients underwent standard MRI protocol and diffusion weighted MR imaging of urinary followed by transurethral cystoscopy. Then transurethral resection of the bladder tumor (TURBT) or radical cystectomy according to the tumor staging with histological examination of resected specimens. Results:Correlation between MR and cystoscopy showing 100% sensitivity in detection of the lesions and as regard to MRI staging of bladder carcinoma and histopathological results the study revealed that 38 patients (86.3%) had the same T stage while 6 patients (13.6%) were overstaged.  Conclusion:DWI have very high sensitivity in detection of the bladder lesions with accurate predictions of the T staging of bladder carcinoma can be made by means of DWI.

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