Correlation of COVID-19 and development of new onset diabetes mellitus and its possible pathogenesis

Articles in Press

Document Type : Original Article

Authors

1 Department of internal medicine, Faculty of medicine, Benha University

2 M.B.B.CH of internal medicine, Faculty of medicine, Alexandria University

3 Department of internal medicine, faculty of medicine, Benha university, Benha, Egypt

Abstract

Background: The severe acute respiratory syndrome-coronavirus (SARS-CoV)-2 was the cause of the pandemic known as coronavirus disease-19 (COVID-19). One of the main metabolic diseases that contribute to death and morbidity worldwide is diabetes. This study aims to evaluate the likelihood of developing new-onset diabetes mellitus in COVID-19-infected patients and its possible pathogenesis. Patients and Methods: This cross-sectional study was conducted at Ashmoun Fever Hospital and Menouf Fever Hospital on 100 cases with confirmed COVID-19 admitted and managed in an inpatient ward and isolated ICU department for 6 months started in December 2020 to July 2021. Results: This study enrolled 100 cases with confirmed COVID-19. There was a highly significant variance between severe to critical than in the mild to moderate group about age, male gender, ICU admission, death, CRP, d dimer, ferritin, FBG, and HbA1c as they were higher in severe to critical than in mild to moderate. There was a high statistically significant relation between FBG and Duration of ICU, Ferritin, Smoking, Cholesterol, TG, HDL, LDL, HbA1C, D-dimer, and severity of COVID-19. Conclusion: Hyperglycemia was linked to poor outcomes in COVID-19 cases. Baseline hyperglycemia levels were a major predictor for mortality among cases admitted immediately to the ICU.

Keywords

Benha Medical Journal

Articles in Press, Accepted Manuscript
Available Online from 01 November 2025

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